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ARTHROSE PNEUMOLOGIE GASTRO ENTEROLOGIE RHUMATOLOGIE

alzheimer

Sous-titre de la section

1 La therapie du dr Willem dont il dit qu'il a guéri des alzheimer: HE huile essentielle de de romarin à cineole. sentir plusieurs fois par jour

2 orotate de lithium 5mg 1/j

3 autres aidants moins appréciés: ginko biloba

Aromatherapy improves cognitive dysfunction in senescence-accelerated mouse prone 8 by reducing the level of amyloid beta and tau phosphorylation.

Michiaki Okuda  +5 more

14 Oct 2020-PLOS ONE

https://typeset.io/pdf/aromatherapy-improves-cognitive-dysfunction-in-senescence-3d7ywql5cc.pdf

 

Essential Oils as Treatment Strategy for Alzheimer's Disease: Current and Future Perspectives.

Anju Benny  +1 more

01 Feb 2019-Planta Medica

https://typeset.io/pdf/essential-oils-as-treatment-strategy-for-alzheimer-s-disease-wahcsw5gsw.pdf

 

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Effect of aromatherapy on patients with Alzheimer's disease

D Jimbo, Y Kimura, M Taniguchi, M Inoue… - …, 2009 - Wiley Online Library

… had Alzheimer's disease (AD). Methods: After a control period of 28 days, aromatherapy was… Aromatherapy consisted of the use of rosemary and lemon essential oils in the morning, …

 

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[HTML] hindawi.comFull View

[HTML] Aromatherapy and aromatic plants for the treatment of behavioural and psychological symptoms of dementia in patients with Alzheimer's disease: clinical …

D Scuteri, LA Morrone, L Rombolà, PR Avato… - Evidence-Based …, 2017 - hindawi.com

… Therefore, there is growing interest, supported by clinical evidence, in aromatherapy for the… to understand the pharmacological basis of aromatherapy in the treatment of BPSDs and to …

 

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[PDF] cell.comFull View

[PDF] Aromatherapy for the brain: Lavender's healing effect on epilepsy, depression, anxiety, migraine, and Alzheimer's disease: A review article

NH Bavarsad, S Bagheri, M Kourosh-Arami, A Komaki - Heliyon, 2023 - cell.com

… Alzheimer's disease (AD) in 7.7 million new cases who develop the disease every year. The… Aromatherapy is effective in reducing depression in postmenopausal women, cases with …

 

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A systematic review of the use of aromatherapy in treatment of behavioral problems in dementia

JKKM Fung, HWH Tsang… - Geriatrics & gerontology …, 2012 - Wiley Online Library

… A paper was included if it was a prospective RCT and had a clinical application of aromatherapy(or essential oils) on people with dementia (or Alzheimer's Disease). RCT in the present …

 

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[PDF] researchsquare.com

Effect of aromatherapy in patients with Alzheimer's disease: a randomised controlled clinical trial

L Lin, R Duan, QH Yang, TT Li, H Zhou, JX Hou… - 2022 - researchsquare.com

… of aromatherapy in the treatment of Alzheimer’s disease (AD) in China, this study aimed toinvestigate the effect of aromatherapy … randomly allocated to aromatherapy groups and control …

 

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[PDF] plos.org

Aromatherapy improves cognitive dysfunction in senescence-accelerated mouse prone 8 by reducing the level of amyloid beta and tau phosphorylation

M Okuda, Y Fujita, Y Takada-Takatori, H Sugimoto… - PLoS …, 2020 - journals.plos.org

… disease and is known to be the most common cause of dementia. We previously describedthe benefits of aromatherapy on … Is the Subject Area "Alzheimer's disease" applicable to this …

 

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[PDF] researchgate.net

[PDF] Aromatherapy in the treatment of Alzheimer's disease: a systemic review

A Banerjee, S Satish, PP Hitendraprasad… - Int. J. Pharm. Sci …, 2021 - researchgate.net

… It's over that aromatherapy provides a … , aromatherapy has provided the most effective proof,together with psychological treatment, for the management of agitation in Alzheimer disease.…

 

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Dementia Prevention and Aromatherapy in Japan.

Urakami K. Yonago Acta Med. 2022 Aug 1;65(3):184-190. doi: 10.33160/yam.2022.08.001. eCollection 2022 Aug. PMID: 36061582 Free PMC article. Review.

In addition to the introduction of a global initiative in dementia prevention, I also introduce the results of our research on the development of the Tottori method dementia prevention program and aromatherapy to approach olfactory impairment in Alzheimer's …

Aromatherapy and Aromatic Plants for the Treatment of Behavioural and Psychological Symptoms of Dementia in Patients with Alzheimer's Disease: Clinical Evidence and Possible Mechanisms.

Scuteri D, Morrone LA, Rombolà L, Avato PR, Bilia AR, Corasaniti MT, Sakurada S, Sakurada T, Bagetta G. Evid Based Complement Alternat Med. 2017;2017:9416305. doi: 10.1155/2017/9416305. Epub 2017 Mar 30. PMID: 28465709 Free PMC article. Review.

The treatment of agitation and aggression, typical Behavioural and Psychological Symptoms of Dementia (BPSDs) of Alzheimer's Disease (AD), is one of the most complicated aspects of handling patients suffering from dementia. ...Therefore, there is growing inte …

fibromyalgie

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·         régime sans gluten, sans lactose, ou en réduisant les sucres et les aliments transformés. La micronutrition (supplémentation en magnésium, vitamine D, coenzyme Q10, probiotiques) est également très populaire avec de nombreux retours d'expérience positifs.  

o        Slomski, A. (2019). Low-FODMAP Diet Reduces Symptoms of Irritable Bowel Syndrome. JAMA. (Le lien avec la fibromyalgie est souvent fait en raison de la forte comorbidité avec le syndrome de l'intestin irritable).

o        Menzies, V., et al. (2020). The Role of Diet in the Development and Management of Fibromyalgia. The Journal for Nurse Practitioners.

Pink Sugar

parkinson

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Mucuna Pruriens (Pois Mascate)

coenzyme Q10

o        Cilia, R., et al. (2017). Mucuna pruriens in Parkinson disease: A double-blind, randomized, controlled, crossover study. Neurology.

o        Katzenschlager, R., et al. (2004). Mucuna pruriens in Parkinson's disease: a double blind clinical and pharmacological study. Journal of Neurology, Neurosurgery & Psychiatry.

o        The Parkinson Study Group QE3 Investigators. (2014). A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease. JAMA Neurology.

Coenzyme Q10 (CoQ10)

o        The Parkinson Study Group QE3 Investigators. (2014). A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease. JAMA Neurology.

ENDOCRINOSyndrome des Ovaires Polykystiques (SOPK)

myo-inositol  

o        Unfer, V., et al. (2017). Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials. Endocrine Connections.

o        Minozzi, M., et al. (2013). The effect of a combination therapy with myo-inositol and a combined oral contraceptive pill versus a combined oral contraceptive pill alone on metabolic, endocrine, and clinical parameters in polycystic ovary syndrome. Gynecological Endocrinology.

o         

·         Réf. clés : revue systématique/meta inositol PCOS. PMC

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cinnamon (cannelle), alpha lipoic acid,(ALA), Ashwagandha (Withania somnifera) — hypothyroïdie subclinique, , Vitamine D (PCOS, diabète, troubles auto-immuns thyroïdiens), DHEA (déhydroépiandrostérone),, N-acetylcysteine (NAC), alpha-lipoic acid, carnitine (compléments métaboliques), Phytothérapies pour hyperandrogénie / hirsutisme (spearmint, saw palmetto etc.)

GASTRO ENTERO

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Probiotiques et Prébiotiques

  1. Ford, A. C., Harris, L. A., Lacy, B. E., Quigley, E. M., & Moayyedi, P. (2018). Systematic review with meta-analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome. Alimentary Pharmacology & Therapeutics, 48(10), 1044–1060.

  2. Goldenberg, J. Z., Yap, C., Lytvyn, L., Lo, C. K., Beardsley, J., Mertz, D., & Johnston, B. C. (2017). Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database of Systematic Reviews, (12).

Transplantation fécale (FMT)

Berbérine

  1.  Chen, C., Tao, C., Liu, Z., Lu, M., Pan, Q., Zheng, L., ... & Yang, J. (2015). A randomized clinical trial of berberine hydrochloride in patients with diarrhea-predominant irritable bowel syndrome. Phytotherapy Research, 29(11), 1822–1827.

  2. Ghabri, S. Z., & El-Mas, M. M. (2022). Berberine: a promising drug for the management of irritable bowel syndrome. Journal of Pharmacy and Pharmacology, 74(3), 329-340.

Curcuma / curcumine

  1. Grammatikopoulou, M. G., Gkiouras, K., & Gkikas, P. D. (2020). Curcumin and Tinospora cordifolia in the treatment of ulcerative colitis: A systematic review and meta-analysis of randomized controlled trials. Phytotherapy Research, 34(10), 2533-2544.

  2. Singla, V., Mouli, V. P., Garg, S. K., Rai, T., & Ahuja, V. (2014). Induction of remission with combination of curcumin and mesalamine in patients with mild-to-moderate ulcerative colitis: a randomized, controlled, pilot study. Journal of Clinical Gastroenterology, 48(3), 226–232.

Menthe poivrée (huile essentielle) Huile de Menthe Poivrée (en gélules gastro-résistantes)

  1. Alam, M. S., Roy, P. K., & Khalique, A. (2022). Peppermint oil for irritable bowel syndrome: a systematic review and meta-analysis of randomized controlled trials. Journal of Clinical Gastroenterology, 56(8), 654-666.

  2. Ford, A. C., Talley, N. J., Spiegel, B. M., Foxx-Orenstein, A. E., Schiller, L., Quigley, E. M., & Moayyedi, P. (2008). Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis. BMJ, 337, a2313.

Régime low-FODMAP (diététique

Zinc-L-carnosine — muco-protection gastrique

Glutamine (complément) — perméabilité  intestinale

Rifaximin (ré-emploi d’un antibiotique non absorbé) — IBS-D / SIBO

Régime pauvre en FODMAPs

  1. Halmos, E. P., Power, V. A., Shepherd, S. J., Gibson, P. R., & Muir, J. G. (2014). A diet low in FODMAPs reduces symptoms of irritable bowel syndrome. Gastroenterology, 146(1), 67–75.e5.

  2. Staudacher, H. M., & Whelan, K. (2017). The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in irritable bowel syndrome. Gut, 66(8), 1517–1527.

Références Scientifiques :

  1. Chen, C., Tao, C., Liu, Z., Lu, M., Pan, Q., Zheng, L., ... & Yang, J. (2015). A randomized clinical trial of berberine hydrochloride in patients with diarrhea-predominant irritable bowel syndrome. Phytotherapy Research, 29(11), 1822–1827.

  2. Ghabri, S. Z., & El-Mas, M. M. (2022). Berberine: a promising drug for the management of irritable bowel syndrome. Journal of Pharmacy and Pharmacology, 74(3), 329-340.

REGIME SEGNALET

ARGILE VERTE

'Comment J'ai Vaincu La Douler Et L'Inflammation Chronique Par L'alimentation'by J Lagancé

C Ciacci - Translational Medicine@ UniSa, 2012 - pmc.ncbi.nlm.nih.gov

… Should this metanalysis been cited along with the others which sustained the miraculous
effect of the Seignalet diet? I believe that the question: “can a certain diet can be of help in …

 

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[PDF] academia.edu

Effects of a very low-fat, vegan diet in subjects with rheumatoid arthritis

J McDougall, B Bruce, G Spiller… - The Journal of …, 2002 - liebertpub.com

… with diet was fashionable in the 1920s and over the past 20 years many reports and studies
have shown benefit for patients who change their diet. Benefits from dietary manipulation …

 

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[PDF] sciencedirect.com

Factors associated with dietary practices and beliefs on food of patients with rheumatic and musculoskeletal diseases: a multicentre cross-sectional study

D Renard, S Tuffet, P Dieudé, P Claudepierre… - Joint Bone Spine, 2025 - Elsevier

… least one exclusion diet (mostly cow's milk- and gluten-free diets in IA, mostly cow's milk-free
diet and detox/fasting in HOA). Only 5% of patients followed the Mediterranean diet. Among …

 

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[CITATION] Diet, fasting, and rheumatoid arthritis.

J Seignalet - Lancet (London, England), 1992 - europepmc.org

… Diet, fasting, and rheumatoid arthritis. Seignalet J … This is a comment on "Controlled
trial of fasting and one-year vegetarian diet in rheumatoid arthritis." Lancet. 1991 Oct 12;338(8772):899-902. …

 

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[PDF] nih.gov

'Comment J'ai Vaincu la Douler et l'Inflammation Chronique Par l'Alimentation'by J Lagacè

G Scarpati, M Pintore - Translational Medicine@ Unisa, 2013 - pmc.ncbi.nlm.nih.gov

… different pathologies and results Seignalet have observed his patients … Seignalet, our genetic
heritage from the Paleolithic hunter-gatherers did not have time to adapt to the modern diet…

 

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[PDF] unisa.it

[PDF] " Comment j'ai vaincu la douler et l'inflammation chronique par l'alimentation" by J Lagacé

C Ciacci - 2012 - elea.unisa.it

… Should this metanalysis been cited along with the others which sustained the miraculous
effect of the Seignalet diet? I believe that the question: “can a certain diet can be of help in …

 

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[CITATION] BOOK REVIEW:'COMMENT J'AI VAINCU LA DOULER ET L'INFLAMMATION CHRONIQUE PAR L'ALIMENTATION'BY J LAGANCÉ

C Ciacci - europepmc.org

… Should this metanalysis been cited along with the others which sustained the miraculous
effect of the Seignalet diet? I believe that the question:“can a certain diet can be of help in …

 

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[LIVRE] The End of Pain: How Nutrition and Diet Can Fight Chronic Inflammatory Disease

J Lagacé - 2014 - books.google.com

… of the Seignalet diet because a good understanding of the scientific principles behind this diet
… Seignalet’s diet on my quality of life as a whole, I will provide a detailed description here of …

 

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[CITATION] Résultats préliminaires d'un régime sans blé et sans lait dans la polyarthrite rhumatoïde

J Seignalet, C Pauthe, J Reynier… - La Presse médicale …, 1989 - pascal-francis.inist.fr

… Other title Preliminary results of a wheat-free and milk-free diet in rheumatoid arthritis (en)
Author SEIGNALET, J 1 ; PAUTHE, C; REYNIER, J; MOENS, P; SIMON, L … Deficient diet …

 

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Psoriasis: ce qu'il faut manger pour réduire les symptômes

MCR Bonjean-Diététicienne-nutritionniste - lanutrition.fr

… Le régime Seignalet Jean Seignalet est un chercheur français qui a donné son nom à un
régime … Dans sa pratique, confirmée par divers essais cliniques par la suite, le Dr Seignalet a …

endocrino  glycemie, thyroide

Sous-titre de la section

CONTROLE GLYCEMIE

 

La Berbérine o        Lan, J., et al. (2015). Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. Journal of Ethnopharmacology.   ---------Zhang, Y., et al. (2020). Treatment of Type 2 Diabetes and Its Complications with Berberine. Journal of Agricultural and Food Chemistry.

Chrome        Suksomboon, N., et al. (2017). Systematic review and meta-analysis of the effect and safety of cinnamon supplementation in people with type 2 diabetes. Journal of Medicinal Food.

​THYROIDE

Le Régime "Anti-inflammatoire" ou "AIP" (Autoimmune Protocol)

o        Inflammatory Bowel Disease. Inflammatory Bowel Diseases. (Étude sur une autre maladie auto-immune, montrant le potentiel du régime).

o        Konijeti, G. G., et al. (2017). Efficacy of the Autoimmune Protocol Diet for Inflammatory Bowel Disease. (L'étude princeps sur le sujet, bien que concernant une autre maladie, est souvent citée pour valider le concept).

o        Il est difficile de trouver des études de grande ampleur spécifiquement sur Hashimoto, la recherche étant émergente.

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selenium

o        Wichman, J., et al. (2016). Selenium Supplementation in Patients with Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis. Thyroid.

o        Toulis, K. A., et al. (2010). Selenium supplementation in the treatment of Hashimoto's thyroiditis: a systematic review and a meta-analysis. Thyroid.

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Pink Sugar

pneumologie

Sous-titre de la section

Colchicine (repurposing) — anti-inflammatoire

Ivermectine

Glutathion inhalé / IV / oral (antioxydant pour maladies respiratoires, CF, etc.)

Hyperbaric Oxygen Therapy (HBOT)

Hyperbaric Oxygen Therapy (HBOT)

Ozone therapy & perfusions d’ozone, inhalation d’ozone

Inhalation / nébulisation d’eau oxygénée (hydrogen peroxide) — tendance dangereuse

Nébulisations de solution salée hypertonique (3% HS) — bronchiolites, mucociliaire

Inhaled corticosteroids (budesonide) —

psychiatrie

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  • Les Acides Gras Oméga-3 (EPA & DHA) Firth, J., et al. (2019). The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta-review of meta-analyses of randomized controlled trials. World Psychiatry, 18(3), 308-324.

Guu, T. W., et al. (2019). A multi-national, multi-center, randomized, double-blind, placebo-controlled clinical trial of the efficacy and safety of an ethyl-eicosapentaenoic acid (E-EPA) formulation (Icosapent ethyl) in major depressive disorder. Journal of Affective Disorders, 257, 1-9.

Probiotiques et Psychobiotiques (Axe Intestin-Cerveau)

  • Wallace, C. J., & Milev, R. (2017). The effects of probiotics on depressive symptoms in humans: a systematic review. Annals of General Psychiatry, 16(1), 14.

  • Liu, L., et al. (2019). The role of the gut microbiome in mediating the effect of education on depression. Molecular Psychiatry, 24(10), 1546-1554.

N-Acétylcystéine (NAC)

  • Deepmala, et al. (2015). N-acetylcysteine for the treatment of psychiatric disorders: a review of current evidence. Journal of Psychiatric Research, 62, 5-11.

  • Minarini, A., et al. (2017). N-acetylcysteine in the treatment of psychiatric disorders: a review of the evidence. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 72, 1-8.

Psychedelic-assisted psychotherapy — psilocybine (dépression, détresse de fin de vie, MDD)

 MEDITATIOn

MDMA-assisted psychotherapy (PTSD)

Psychedelic microdosing (LSD/psilocybine à très faible dose)

tDCS (stimulation transcranienne à courant continu)

rTMS / TBS (stimulation magnétique répétée)

Cannabidiol (CBD) pour anxiété / PTSD / sommeil

  • Blessing, E. M., et al. (2015). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics, 12(4), 825-836.

  • Shannon, S., et al. (2019). Cannabidiol in anxiety and sleep: a large case series. The Permanente Journal, 23.

) St John’s Wort (Hypericum perforatum) — dépression légère-modérée

S-adenosyl-methionine (SAM-e) )

Lithium « microdosing » / bas-dose lithium (neuroprotection, suicidality)

Neurofeedback / biofeedback (HRV, EEG, fMRI NF)

  • Hofmann, S. G., et al. (2010). The effect of mindfulness-based therapy on anxiety and depression: A meta-analytic review. Journal of Consulting and Clinical Psychology, 78(2), 169-183.

  • Kuyken, W., et al. (2016). Efficacy of mindfulness-based cognitive therapy in prevention of depressive relapse: a systematic review and meta-analysis. JAMA Psychiatry, 73(6), 565-574.

Light therapy & chronobiologie (SAD, dépression saisonnière, dépression mélancolique) ) Luminothérapie

  • Golden, R. N., et al. (2005). The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence. American Journal of Psychiatry, 162(4), 656-662.

  • Al-Karawi, D., & Jubair, L. (2016). Bright light therapy for nonseasonal depression: a systematic review. The Journal of Nervous and Mental Disease, 204(8), 569-575.

) Exercise, sommeil, nutrition (omega-3, vit D), psychothérapie intégrative

Phytothérapie Le Millepertuis (Hypericum perforatum) SAFRAN, brigonia et beaucoup d’autres plantes

  • Apaydin, E. A., et al. (2016). A systematic review of St. John's wort for major depressive disorder. Systematic Reviews, 5(1), 148.

Ng, Q. X., et al. (2017). Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis. Journal of Affective Disorders, 210, 211-221

Repurposing de Médicaments (Repositionnement) Minocycline Aspirine et autres anti-inflammatoires (AINS Kétamine (en hospitalier/ danger)

Köhler-Forsberg, O., et al. (2019). Efficacy of anti-inflammatory treatment on major depressive disorder or depressive symptoms: meta-analysis of clinical trials. Acta Psychiatrica Scandinavica, 139(5), 413-425.

EFT, EMDR

rajeunissement

Le NAD+ et ses Précurseurs (Nicotinamide Riboside - NR, Nicotinamide Mononucleotide - NMN)

  • Sinclair, D. A. (2019). Lifespan: Why We Age – and Why We Don't Have To. Un livre de vulgarisation par un chercheur de dans .

  • Martens, C. R., et al. (2018). Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nature .

Irie, J., et al. (2020). Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men. Endocrine Journal

 

Metformine (Repurposing de Médicament) Metformine (Repurposing de Médicament)

  • Barzilai, N., et al. (2016). Metformin as a Tool to Target Aging. Cell Metabolism.

Kulkarni, A. S., et al. (2018). Metformin in prevention and treatment of aging and aging-related diseases: a systematic review. Expert Review of Clinical Pharmaco

. Le Resvératrol

  • Sinclair, D. A., et al. (2006). Resveratrol improves health and survival of mice on a high-calorie diet. Nature.

Turner, R. S., et al. (2015). A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer's disease. Neurology.

La Restriction Calorique et le Jeûne Intermittent

  • Longo, V. D., & Mattson, M. P. (2014). Fasting: molecular mechanisms and clinical applications. Cell Metabolism.

de Cabo, R., & Mattson, M. P. (2019). Effects of Intermittent Fasting on Health, Aging, and Disease. The New England Journal of Medicine.

 

Senolytiques (ex. dasatinib + quercétine, fisétin, navitoclax)

Rapamycine / inhibiteurs mTOR (sirolimus, everolimus)

 

Spermidine (autophagy inducer)

Telomerase activators (TA-65 et dérivés)

Plasma jeune / « young plasma » / facteurs circulants

Thérapies cellulaires / exosomes (cellules souches, injections) pour rajeunissement tissulaire

 Epigenetic reprogramming (facteurs Yamanaka, reprogrammation partielle)

Caloric restriction (CR), intermittent fasting (IF) et interventions « hormesis » (sauna, froid, exercice)

Hyperbaric oxygen therapy (HBOT) — usages « rajeunissants »

Peptides & petit-molecule « biohack » (GHRH fragments, thymosins, BPC-157, FOXO modulators, etc.)

Mitochondrial enhancers (CoQ10, PQQ, mitoQ)

Cryothérapie, sauna & thermothérapie (adaptation au stress)

Antioxydants classiques, vitamines (vit C/E) et « super-antioxydants »

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